Abstract
PHARMACOGNOSTICAL AND PHARMACEUTICAL ANALYSIS OF JATAMANSYADI TABLET

Shreyas R Adhvaryu*, Alankruta R Dave, Mandip Goyal, Harisha C R and V J Shukla

ABSTRACT

Essential Hypertension (EHT) is one of those disastrous diseases which are psychosomatic, hereditary and occurring as a result of aging. Jatamansyadi Tablet is a compound herbal formulation which contains Jatamansi, Gokshura, Arjuna, Aswagandha and Brahmi in equal proportion. The present work was carried out to standardize Jatamansyadi Tablet to conform its identity, quality and purity. For these purpose Pharmacognostical evaluation based on organoleptic and microscopic characteristics and Pharmaceutical analysis of Jatamansyadi Tablet was carried out. The presence of Oil globules, Scleriform vessels, Rosette crystal, Tannin content, Simple Starch Grain, Border Pitted Vessels, Prismatic crystal, Annular vessels etc. were the characteristic features observed in the microscopy of drugs. Physico-chemical analysis shows water soluble extract 31.1% w/w, methanol soluble extract 31.3% w/w, total ash content 32.7% w/w and pH 4.5. Tablet Hardness 4.1 kg/cm2 and Tablet uniformity was 541 mg. High Performance Thin Layer Chromatography (HPTLC) at 254nm and 366nm resulted into 14 & 11 spots respectively.

Keywords: HPTLC, Hypertension, Jatamansyadi Tablet, Pharmaceutical, Pharmacognosy.


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