Abstract
RECENT ADVANCES ON RECOMBINANT ANTIGENS FOR CONTROLLING PARASITIC PROTOZOA: DIAGNOSIS AND VACCINE DESIGN

Abbas Alibakhshi, Hajar Yaghoobi, Mojgan Bandehpour* and Bahram Kazemi

ABSTRACT

Parasitic protozoa cause important diseases with a worldwide distribution. Although significant advancements in recognition of etiology of parasitic diseases have been made, there are still obstacles in their control. Hence, prevention and diagnosis are of major importance in such serious pathogenic diseases. Most of the methods for control of parasitic protozoa are based on lysate antigens. Many studies also show that recombinant antigenic proteins may be very useful alternatives for serodiagnosis and vaccine design of parasitic protozoa. In this review, current and recent studies on usefulness of parasite recombinant antigens in diagnosis tests and vaccine development for human are described.

Keywords: Recombinant antigens, Diagnosis, Vaccine, Parasitic protozoa.


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