CHANGES IN PLATELET AND PLATELET INDICES DURING PREGNANCY AS POTENTIAL MARKERS FOR PREDICTION OF PREECLAMPSIA DEVELOPMENT, 2016
Mervit Hassan* and Dr. Enaam Abdelrahman Abdelgader
ABSTRACT
Background: Platelets, also called thrombocytes, are a component of blood whose function (along with the coagulation factors) is to stop bleeding by clumping and clotting blood vessel injuries. Preeclampsia is a condition that pregnant women develop. It is marked by high blood pressure in women who have previously not experienced high blood pressure before. Objective: The purpose of this study was to assess the role of platelet count and platelet indices as marker for development of Preeclampsia. Materials and Methods: Eighty samples included in this study, 50 were pregnant women with Preeclampsia and other 30 as a control group were evaluated to determine the changes in Platelets and platelet indices among pregnant women with Preeclampsia. The platelet count and indices was determined using Sysmex® Kx21-N Analyzer. Results: The Platelets count (mean +/- SD) were 246.4 (± 55.8) in pregnant women with Preeclampsia and 284 (± 65.03) in control group, Platelets were significantly Lower in pregnant women with Preeclampsia (P=0.002). Platelet indices showed no significant change between two groups (P> 0.05). Conclusion: A among the Platelets count and platelet indices, Platelet count is considered to be an ideal early monitoring index for pre-eclampsia and potential marker for predicting the severity of pre-eclampsia in early pregnancy.Background: Platelets, also called thrombocytes, are a component of blood whose function (along with the coagulation factors) is to stop bleeding by clumping and clotting blood vessel injuries. Preeclampsia is a condition that pregnant women develop. It is marked by high blood pressure in women who have previously not experienced high blood pressure before. Objective: The purpose of this study was to assess the role of platelet count and platelet indices as marker for development of Preeclampsia. Materials and Methods: Eighty samples included in this study, 50 were pregnant women with Preeclampsia and other 30 as a control group were evaluated to determine the changes in Platelets and platelet indices among pregnant women with Preeclampsia. The platelet count and indices was determined using Sysmex® Kx21-N Analyzer. Results: The Platelets count (mean +/- SD) were 246.4 (± 55.8) in pregnant women with Preeclampsia and 284 (± 65.03) in control group, Platelets were significantly Lower in pregnant women with Preeclampsia (P=0.002). Platelet indices showed no significant change between two groups (P> 0.05). Conclusion: A among the Platelets count and platelet indices, Platelet count is considered to be an ideal early monitoring index for pre-eclampsia and potential marker for predicting the severity of pre-eclampsia in early pregnancy.
Keywords: Platelets, Preeclampsia, MPV, PDW, P-LCR.
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