Abstract
ANTIMICROBIAL, ANTIOXIDANT AND CYTOTOXICITY ACTIVITY OF PIGMENT PRODUCED FROM SERRATIA MARCESCENS

Dr. K. P. Renukadevi* and M. Vineeth

ABSTRACT

Pigments from Serratia marcescens were characterized by GC-MS. Serratia marcescens pigment showed good antibacterial activity against Clostridium sp, E.coli, Citrobacter ferundii, Calvibater sp, and Enterobacter amingences. These pigments showed strong antioxidant activity by DPPH radical scavenging assay. The pigment was found to exhibit cytotoxicity activity against the Breast cancer cell line MCF-7. Cytotoxicity was determined by MTT assay. Thus on increasing the concentration of the pigment extract, the percentage of the cell viability was found to be reduced. These properties of pigment can be used in the development of drugs for cancers.

Keywords: Pigments, GC-MS, DPPH method, MTT assay, Antimicrobial activity, Antioxidant activity, Cytotoxicity activity.


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