European Journal of Biomedical and Pharmaceutical Sciences

SCIENTIFIC EVALUATION OF LAVANGADI CURNA –A CLASSICAL AYURVEDIC COMPOUND FORMULATION

Manoj Kumar Tripathi*, Neelesh Kumar Dwivedi and Ashok Kumar Tiwari

ABSTRACT

Ayurveda comprises of various types of medicines including asavas (fermented infusions), arishtas (fermented decoctions), Curnas (fine powder) and Kvatha curnas (coarse powder). These are regarded as valuable therapeutics due to their efficacy and desirable features. Identification and quality evaluation of crude drugs is a fundamental requirement of industry and other organizations dealing with natural health products. Thus, there is an urgent need to evaluate such parameters which can be adopted by the pharmaceutical industries. In the present communication attempts have been made to standardize Lavangadi curna a classical Ayurvedic compound formulation which is used to treat Grahaṇi (malabsorption syndrome); atisãra (diarrhoea); ãmãtisara (diarrhoea due to indigestion); raktatisãra ( diarrhoea with blood); sula (pain); sotha (inflammation) and formulated by twenty five ingredients viz. Lavanga (Syzygium aromaticum (Linn.) Merr. & M. Perry.- Flower bud), Tankaṇa (śuddhã), Musta (mustã) (Cyperus rotundus Linn.- Rhizome), Dhãtakî (Wood-fordia fruticosa Kurz.-Flower), Bilva (Aegle marmelos Corr.- Fruit pulp), Dhãnyaka (Coriandrum sativum Linn.-Fruit), Sarjika (Vateria indica Linn.- Exd.), Jãtiphala (Myristica fragrans Houtt.-Fruit), Śatãhvã (Anethum sowa Kurz.-Fruit), Dãḍima (Punica granatum Linn.-Fruit), Jîraka (śvetajîraka) (Cuminum cyminum Linn.-Fruit), Saindhava (Rock salt), Moca ( śãlamalî) (Salmalia malabarica Schott & Endl.- Exd.), Nilotpala (utpala)( Nymphasa stellata Wild.-Flower), Rasãnjana (dãruharidrã) ( Berberis aristata DC.- Exd.), Abhraka bhasma, Vanga bhasma, Samangã (lajjãlu) (Mimosa pudica Linn.-Root), Rakta candana (Pterocarpus santalinus Linn. F. – Heart wood), Cavya (Piper chaba Hunter-Stem), Ativiṣã (Aconitum heterophyllum Wall.-Root), Sṛngî (karkaṭaśṛngî) (Pistacia integerrima Burgo- Gl.), Khadira (Acacia catechu Wild.-Heart wood), Bãlaka (hrîvera) (Coleus vettiveroides K.C. Jacos.-Root), Bhṛngarãja (svarasa) (Eclipta alba Husk-Whole plant). Three samples procured from different manufacturers were subjected to HPTLC fingerprinting and physicochemical analysis was done. Physicochemical parameters average value of total ash 13%, acid insoluble ash 4%, alcohol soluble extractive 14%, water soluble extractive 35%,); pH (10 % aqueous solution): 5 to 6 and loss on drying at 1050c 7%. It was observed that the chromatographic analysis complements each other in their findings and can be used effectively for the identification of raw materials in the compound formulation.

Keywords: Lavangadi curna, Scientific evaluation, HPTLC fingerprints, Physicochemical analysis.