*Dr. Sanjeev Laller (MDS) Reader, Dr. Kanwalpreet Kaur (Lecturer), Dr. Mamta Malik (MDS) Reader and Dr. Pooja Sheokand (MDS) 


Sir, Ebola virus is one among three genera of Filoviridae family about which the exact causative agent, mode of spread, incubation period and outcome is not known till date. The first outbreak was noticed in Marburg, Germany (1967) when some laboratory workers suffering from an unusual disease were admitted to hospital. The next two simultaneous outbreaks (1976) were noticed in Nazara, Sudan and other in a village near Ebola River in Yambuku, Congo, due to this fact the disease is known by this name. The latest outbreak in West Africa was largest and most complex since its discovery. The commonest causative agent was fruit bats or monkeys/apes. The etiopathogenesis is still under scrutiny but the transmission was found by contact with the bodily fluids of infected animals and humans. By antibody dependent Enhancement mechanism (ADE) the virus first attacks the monocytes and macrophages followed by dendritic cells, endothelial cells and liver cells, attacking host’s immune system.[1]

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