European Journal of Biomedical and Pharmaceutical Sciences

COMBINING SYNERGY OF INDUCTIVELY COUPLED PLASMA MASS- SPECTROPHOTOMETRY (ICP-MS) AND X-RAY POWDER DIFFRACTION (XRPD) FOR HERBAL MEDICINAL PRODUCT OF B. P. C. CAPSULE.

Raju P. Suryawanshi* and Sudhir S. Kamat

ABSTRACT

BPC Capsule is one of the most popular herbal medicines in Indian market for Blood Pressure patients. Electrolytes, Trace elements, Toxic, Essential, Trace metals, Minerals, Alkaloids, Steroids and organic compounds, besides that it also contains enzymes, proteins, and other Inorganic elements are naturally present in herbal medicines. The BPC. Capsule contain, Calcium(Ca), Manganese(Mn) and zinc(Zn). Though they are essential elements it is utmost necessary to determine the quantitatively because it most effects on Blood pressure and kidney. The daily requirement of Calcium(Ca), Manganese(Mn) and zinc(Zn) is in micrograms, but there is no proper method to detect the accurate concentration of essential elements, minerals, electrolytes and Inorganic elements present in herbal medicines. Popularity of herbal medicines is growing worldwide because of their minimal side effects. Herbal medicines required standardization, with implementation and constant review of technical standards of production and effective quality control methods. It is necessary to promote this study in the view of the importance of results of both individual and social field. Diseases occur due to their deficiency and toxicity due to overdose. These Elements can bind to vital cellular components and interfere with their normal functions. In human being, these elements can cause severe physiological and health effects. Therefore, it is thought necessary about the efficacy and standardization of BPC Capsule. These Elements can determine by quantitatively and validated by using modern technique such as ICP-MS (Inductively Coupled Plasma Mass-Spectrophotometry) and XRPD. (X-Ray Powder Diffraction).

Keywords: B. P. C. Capsule, Standardization, Herbal medicine, Standardization, ICP-MS, XRPD, Calcium(Ca), Manganese(Mn) and Zinc(Zn).