European Journal of Biomedical and Pharmaceutical Sciences

ANTIBACTERIAL ACTIVITY OF DIFFERENT EXTRACT OF CURCUMA LONGA IN THE MANAGEMENT OF FISTULA IN ANO

A.A.J.P.Kumara*, D. L. Jayratne and G. V Samaranayake

ABSTRACT

Ayurvedic parasurgical treatment procedure Ksharasutra was one of the effective treatment for management of the fistula in ano. Curcuma longa was the one of the main ingredient in a thread. In the present work an attempt has been made to analyze the antibacterial and potential of methanol, ethanol and aqueous extracts of Curcuma longa against E.coli S. aureus, S.agalactiae and P.aeruginosa among bacterial strains by disc diffusion method and the antibacterial were determined by measuring the diameter of zone of inhibition. The study reports on extraction method using soxhlet extractor The methanol extracts of Curcuma longa possessed the highest antibacterial with a zone of inhibition of 34 mm for, S. aureus and lowest 13mm for P.aeruginosa, ethanol extract has range of zone of inhibition 31mm-10mm while lowest antibacterial activities was reported aqueous extract range 28mm-11mm zone of inhibition.

Keywords: Curcuma longa, Agar well diffusion method Antibacterial activity.