European Journal of Biomedical and Pharmaceutical Sciences

COMPLICATED INFECTIOUS MONONUCLEOSIS IN ?-THALASSEMIA PATIENT, A RARE CASE

Abir Ghaith, MD. Jennifer Abi Younis, MD. Abir AlHoujairy, MD. Imad Chokr, MD Bassem Abou Merhi*, MD.

ABSTRACT

The Epstein–Barr virus (EBV is one of the most common viruses in humans. It is best known as the cause of infectious mononucleosis (Glandular Fever). Infectious mononucleosis, generally results in mild, self-limited illness characterized by fever, sore throat, and lymphadenopathy. Occasionally, EBV infection has more severe sequelae; Lymphoproliferative lesions, Hepatitis, Encephalitis, and Hemolytic Anemia have been reported. Although kidney involvement is relatively common, acute renal failure associated with EBV infection is rare. Acute Tubular Necrosis (ATN) is a kidney disorder involving damage to the tubule cells of the kidneys. This reported case is a twelve year old boy known to have β-Thalassemia major post splenectomy, on packed red blood cell transfusion, developed many complications and his kidney biopsy done and showed acute tubular injury treated with Steroid.

Keywords: Epstein Barr Virus (EBV), Human Herpes Virus (HHV), Acute Tubular Necrosis (ATN).