European Journal of Biomedical and Pharmaceutical Sciences

THYROID DYSFUNCTION IN PATIENTS WITH DIABETES MELLITUS: A RETROSPECTIVE STUDY

Amit Kumar Dixit*, Ranjit Kumar Dey, Rohit Kumar Ravte, Ashok Kumar Panda, Sanatan Rai, Naushin Afrin, Jayram Hazra

ABSTRACT

Thyroid dysfunction is one of the common endocrinopathy encountered in diabetes mellitus, which affects the basal metabolic rate of the individual. Early detection and treatment of thyroid dysfunction in type-2 diabetes mellitus can prevent risk for various metabolic disorders. The rationale of this study was to study the prevalence of thyroid dysfunction in patients with type-2 diabetes mellitus. Necessary data was collected from the medical archives of 60 patients (43 female and 17 male) with diabetes mellitus registered in Department of Pathology and Biochemistry of Ayurveda hospital established at Kolkata, India. The mean ages of female and male subjects were 41.2 ± 5 and 44.2 ± 8 years respectively. Out the 60 diabetes mellitus patients, 36 with euthyroid, 9 with subclinical hypothyroidism, 10 with hypothyroidism, 4 with subclinical hyperthyroidism and 1 with hyperthyroidism were identified. In conclusion, the result suggest that the prevalence of thyroid disorder is quite high in female patients with type-2 diabetes mellitus and most of them have subclinical hypothyroidism, and most of these patients were above 40 years of age. This is a preliminary study with a small sample size, hence, larger epidemiological studies is required to find out the actual prevalence and incidence of thyroid dysfunction in patients with diabetes mellitus.

Keywords: Thyroid dysfunction; diabetes mellitus; triiodothyronine; thyroxine; TSH.