European Journal of Biomedical and Pharmaceutical Sciences

HERBAL GEL CONTAINING CORM EXTRACT OF PISANG KEPOK (MUSA BALBISIANA) PROMOTE HAIR GROWTH OF RABBIT

Mashuri Yusuf, Qurota Aini, Isbiyantoro, Rr Prita Permatasari, Yulianty, Mohammad Kanedi*

ABSTRACT

Current technologies and therapies of hair disorders are not yet satisfying people suffer from hair loss, so that efforts in seeking effective medicine for promoting hair growth are still continues. This study intended to investigate and confirms the effects of crude corms extract of pisang kepok (Musa balbisiana) given topically on rabbit hairs growth. Four healty, male rabbits, aged 4-5 months, weighing 1.5 kg – 2 kg were used for the study. Six areas (2 cm x 2 cm each) on the dorsal aspects of animals were shaved. The first shaved area treated topically with nothing (normal control). The second and third areas treated consecutively with gel without banana corms extract (as negative control) and reference formulations (as positive control). The last three areas treated with gel containing corms extract of pisang kepok with the concentration of 2%, 4% and 8% respectively. All treatments were given once daily for 21 days. The length of hairs were assessed on day 7, 14 and 21, while the hair mass was measured on day 22. The results showed herbal topical gel containing crude corms extract of pisang kepok significantly increase the animal hairs length and mass in comparison to the normal and negative control. Therefore it can be suggested that herbal gel containing corms extract of M. balbisiana is potent to be use as the topical formulations for hair growth.

Keywords: Pisang kepok, Musa balbisiana, hair loss, hair growth promotion, banana corms extract, androgenetic alopecia.