European Journal of Biomedical and Pharmaceutical Sciences

ASSESSMENT OF COPPER AND ZINC IN CARDIOVASCULAR DISEASE (CVD)

Asma Gaafar Osheak* and Omer Fadil Adris

ABSTRACT

Cardiovascular disease (CVD) class of diseases known as heart and circulatory disease. This study was carried out to assess the serum levels of copper and zinc in CVD patients Determination of trace element concentration were carried out on 40 patient with CVD and 40 healthy controls serum copper and zinc were measured by using Atomic Absorption Electro photometer. The mean serum zinc and copper levels in patients with CVD were significantly lower than control groups with P-value (0.000). In contrast the mean levels of ratio Cu\Zn was insignificantly difference in CVD patients, compared to control group (p-value 0.103) [table 3.3] The result of person correlation observed there were no correlation between copper and zinc with duration of disease and age. Low copper could lead to decreased activities of some copper-dependent enzyme. Copper depletion have revealed abnormalities of lipid metabolism, blood pressure control and electrocardiogram plus impaired glucose tolerance. Low zinc effect in immune system and protein synthesis, and lead to abnormal cell growth.

Keywords: CVD, Trace elements, Zinc copper and Sudan.