European Journal of Biomedical and Pharmaceutical Sciences

THE ASSOCIATION OF VITAMIN D DEFICIENCY AND ANEMIA WITH CELIAC DISEASE IN A YOUNG CHILD: A CASE STUDY

Ahmed I. Insaf and Ali S. Dawood*

ABSTRACT

Celiac disease (CD) is an autoimmune disease triggered by the ingestion of foods containing gluten (gliadin), which is associated with vitamin D deficiency and with a number of hematological disorders. Individuals can present with vitamin D deficiency and hematological abnormalities even prior to the diagnosis of celiac disease. We report a typical case of a 13 years old male presented with presented with recurrent attacks of diarrhea, constipation since the age of two years, loss of appetite, fatigue, loss of interest, history of two fracture in the last two years from simple trauma, the patient not responding to the treatment, Further laboratory tests were performed, the complete blood picture showed that the patient suffering from hypochromic microcytic anemia, Hb 8 g/dL, vitamin D3 level was 3.5 ng/ml, anti gliadin IgA test was negative, anti gliadin IgG test was positive (1.9), anti tissue transglutaminase IgA was positive (6.6) and anti tissue transglutaminase IgG was positive (8.1). Our conclusion suggested that, the vitamin D deficiency and anemia in CD are common during the childhood, therefore the screening of further laboratory investigations are needed.

Keywords: Celiac disease, Vitamin D deficiency, Anemia.