CHEMICAL COMPOSITION AND ANTI-CANDIDIASIS ACTION OF SCHINUS TEREBINTHIFOLIUS RADDI (AROEIRA) ESSENTIAL OIL
Mônica Batista Almeida, Daniela Lima Travassos, Patrícia Severino*, Carine Santana Ferreira*, Jessica Oliveira Carvalho, Jane de Jesus da Silva Moreira, Rita de Cassia Trindade and Edilson Divino Araújo
ABSTRACT
Candida species remains the most common cause of human fungal infection. Vaginal candidiasis is difficult to treat and is often resistant to many antifungal drugs. Considering the need to obtain new therapeutic agents aimed at combatting vaginal candidiasis, the objective of this study was to investigate antifungal activity of essential oil Schinus terebinthifolius Raddi in species of Candida species. Schinus terebinthifolius Raddi essential oil was obtained by hydrodistillation and characterized by gas chromatography. The Minimum Inhibitory Concentration (MIC) and Minimal Fungicide Concentration (MFC) were performed based on Clinical and Laboratory Standards Institute. Results showed majority components of essential oil was monoterpenes. Fungistatic action were observed for essential oil extracted from dry fruits and essential oil extracted from fresh leaves or fruits presenting promising results for further research and continuity of the study of this plant. In summary, these demonstrate the potential fungistatic activity of essential oil Schinus terebinthifolius Raddi that may help to explain the popular use in vaginal infection.
Keywords: Medicinal plant; candidiasis; essential oil; Candida spp, Schinus terebinthifolius Raddi.
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