European Journal of Biomedical and Pharmaceutical Sciences

ANTHELMINTIC ACTIVITY OF CURCUMA CAESIA ROXB RHIZOME IN INDIAN ADULT EARTHWORM

Anum Karim, Indrapal Singh, Mohd. Washid Khan* and Reetesh Chourasia

ABSTRACT

Curcuma caesia Roxb, popularly known as black termeric in India belongs to family Zingiberaceae. The objective of the present work was to evaluate the in-vitro anthelmintic potency of the ethyl acetate extract of Curcuma caesia rhizome using Indian earthworms (Pheretima posthumad). The various concentrations (25, 50, and 75 mg/ml) of the ethyl acetate extract were tested in-vitro for anthelmintic potency by determination of time of paralysis and time of death of worm. Albendazole (15mg/ml) used as standard. The result of present study indicates that the Curcuma caesia. potentiate to paralyze earthworm and also caused its death after some time. The shortest time of paralysis was observed at higher dose (75 mg/ml) of ethyl acetate extract was found to 30.86 min. Thus, the present study demonstrate that the Curcuma caesia as an anthelmintic has been confirm as the ethyl acetate extract of leaves displayed activity against the earthworm used in study.

Keywords: Curcuma caesia, Paralysis, death of earthworm.