Abstract
FORMULATION AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF TOPICAL HERBAL DRUG DELIVERY SYSTEM FOR THE TREATMENT OF ACNE VULGARIS BY USING ALCOHOLIC EXTRACTS

Jangme C. M.*, Somnathe N. D., Kshirsagar M. D. and Shivakumar S. Ladde

ABSTRACT

A Novel drug delivery system aim to improve patient compliance, and dispersible are no exception. The dosage forms available for the delivery of topical agents include ointments, pastes, creams, lotions, gels, and powders. Creams are often preferred over the other topical preparations because less irritating and easier to apply. The cooling effect due to evaporation of water gives soothing effect at the inflamed area. The present investigation concerns the developments of formulation and evaluation of efficacious and safe topical herbal drug delivery system for the treatment of Acne Vulgaris by using ethanolic extracts of Azadirachta indica, Amba Haldi and Curcuma Longa. Topical herbal formulation of the plant extract was evaluated for physical parameters, viscosity, Skin Irritation, Spreadibility and antimicrobial activity. The formulations were found to be better in all aspects. Thus it can be used as an alternative for the treatments and drug delivery systems.

Keywords: Topical Herbal Drug Delivery System, Azadirachta indica, Amba Haldi, Curcuma Longa, Acne Vulgaris.


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