European Journal of Biomedical and Pharmaceutical Sciences

CORRELATION OF THYROID STIMULATING HORMONE WITH PROLACTIN, FSH AND LH IN SUDANESE INFERTILE FEMALES

Alhassan M. Alhassan, Suhair A. Ahmed* and Omer F. Idris

ABSTRACT

Introduction: Measurement of prolactin and thyroid hormones, especially thyroid stimulating hormone (TSH), has been considered an important component of infertility work up in women. Thyroid dysfunctions interfere with numerous aspects of reproduction and pregnancy. Objectives: To correlate thyroid stimulating hormones level with FSH, LH and prolactin in infertility in the reproductive age women. Materials and methods: This study included 60 infertile women in reproductive age who attended the infertility clinics. 45 out of them were of primary infertility and 15 of secondary infertility. Thyroid stimulating hormones, prolactin, LH and FSH hormones levels were measured from all participants by TOSOH AIA360 (Fluorescence Enzyme Immunoassay). Results: Hyperprolactinemia was depicted in 21.6% infertile females. Prevalence of primary infertility was 75% while that of secondary infertility was 25% in study group, there was a significant positive correlation between serum TSH and Prolactin levels in infertile women with (p < 0.05) and negative correlation of TSH with LH and FSH. Conclusion: There was higher prevalence of hyperprolactinemia with normal thyroid function in infertile patients.

Keywords: Infertility, Thyroid stimulating hormones, FSH, LH, Prolactin, Sudan.