European Journal of Biomedical and Pharmaceutical Sciences

RELATIONSHIP BETWEEN HYPERTENSION AND LEFT VENTRICULAR HYPERTROPHY: A CLINICAL STUDY DONE AT A TERTIARY CARE CENTRE

Sarah A. M. and Sayeed M. U.*

ABSTRACT

Hypertension is one of the leading risk factor for cardiac diseases. High blood pressure (hypertension) is one of the leading cause of death, causing over 7.5 million deaths and 57 million cases of disability all over the world. It manifests through entire organ systems, including the heart it self. Features of hypertensive heart disease include left ventricular hypertrophy, diastolic and systolic heart failure. As the law of Laplace suggests, left ventricular hypertrophy (LVH) is meant to encompensate excessive systemic blood pressure. Hence, this study was conducted in order to investigate the relationship of hypertension with incidence of left ventricle hyperthrophy on clinical basis. This study is a cross sectional study, involving 50 patients from a Tertiary Care Centre in Medan Indonesia and using secondary data gained from patients medical record. Only LVH diagnosed by means of echocardiography wast taken into consideration and used in this study, considering that echocardiography is the gold standard of LVH diagnosis. Statistical analysis was conducted using Chi – square. In this study, we found that 85.7% of patients with hypertension develop LVH and that hypertension showed significant relationship to the incidence of LVH (p = 0.003 < p = 0.05). Further analysis with ANOVA showed that hypertension class has no significant correlation with the incidence of LVH p = 0.229 ( p > 0.05), thus indicating that there is no proven consistency between hypertension class and LVH.

Keywords: Hypertension, LVH, echocardiography, Laplace’s law.