Abstract
SECONDARY METABOLITES FROM THE LEAVES OF CINNAMOMUM MACROSTEMON HAYATA

Cheng-Ta Li, Chiu-Li Kao, Hsing-Tan Li1, Shu-Ting Huang and Chung-Yi Chen*

ABSTRACT

A chemical investigation of the leaves of Cinnamomum macrostemon Hayata (Lauraceae) afforded fifteen phytochemicals including three butanolides, obtusilactone A (1), isoobtusilactone A (2), and tenuifolide B (3); three coumarins, coumarin (4), isoscopoletin (5), and scopoletin (6); two steroids, β-sitostenone (7), and β-sitosterol (8); two benzenoids, cinnamic acid (9), and eugenol (10); two lignans, (+)-yangambin (11), and (+)-syringaresinol (12); three dibenzocyclo- heptenes, tenuifolin (13), reticuol (14), and subamol (15). The structural elucidation was performed mainly by MS, 1D and 2D NMR spectrum data. Compounds 1-3, 5, 6, 11, 13, and 15 were found for the first time from this plant.

Keywords: Cinnamomum macrostemon Hayata, Lauraceae, butanolides, dibenzocycloheptenes.


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