Abstract
DEVELOPMENT OF A THIN LAYER CHROMATOGRAPHY METHOD FOR THE SEPARATION OF SALBUTAMOL ENANTIOMERS USING CHIRAL MOBILE PHASE ADDITIVES

Houda Chihab, *Dr. Rachid Fegas,  Said Zerkout and Michel Righezza

ABSTRACT

A simple, rapid and accurate thin layer Chromatography method was developed for salbutamol enantiomers in tablet dosage form. The thin layer Chromatography method has shown adequate separation of salbutamol enantiomers in tablet Dosage form. The separation was achieved with mobile phase Acetonitril / Methanol/Cu2+, TLC plates: silica gel and cellulose, L-phenyl analine and histydine as selectors.

Keywords: Salbutamol enantiomers, different TLC plates.


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