European Journal of Biomedical and Pharmaceutical Sciences

DEPRESSION AND ROLE OF MARINE BIOMATERIALS: A REVIEW

Vandita Namola*, Parminder Ratan and Preeti Kothiyal

ABSTRACT

Depression is the most common disorder nowadays seen in adults, old age and even children. It is one of the largest causes of morbidity, and is often accompanied with low mood, loss of appetite, insomnia. The major factors contributing to depression is deficiency of monoamines such as serotonin, noradrenaline, dopamine in various regions of the brain. The rapidly growing number of patients suffering from depression has lead to an enormous increase in the research on antidepressant drugs, and as it is well known that synthetic drugs have various side effects therefore research on natural sources for treatment of depression is going on and marine sources being the most diverse of all natural sources is being studied extensively. Marine Biomaterials such as Bryostatin , and other biomaterials obtained from crustaceans , seaweed , algae are currently being researched as antidepressant leads . Hence, the objective of this review is to discuss various marine biomaterials that can serve as potent antidepressants.

Keywords: Depression, Monoamines, MAO, Marine biomaterials.