Abstract
ASSESSMENT OF VOLUME AND ACTIVITY OF CLOTTING FACTORS IN FRESH FROZEN PLASMA PRODUCED FROM WHOLE BLOOD IN BLOOD BANK

Wamda Ahmed Gourashi and Abdel Rahim Mahmoud Muddathir*

ABSTRACT

Introduction: Plasma is the aqueous component of blood, Fresh-frozen plasma (FFP) is one of the plasma products frequently used to treat minor to major coagulation factor deficiency. The present study assessed the quality of prepared (FFP) by measuring the whole volume of FFP, concentration of FV, FVIII and fibrinogen. Materials and Methods: This was descriptive cross sectional study done in two blood bank hospitals at Khartoum state–Sudan, during the period December 2014 to February 2015, in which a total of 100 triple blood bags collected from blood donors and fresh plasma was extracted. From each prepared plasma bags FV, FVIII and fibrinogen were measured on Dia Lab Coagulometer Analyzer™, also the volume of the prepared plasma bags have been determined. Results and discussion: The study revealed that the activity of FV= 111.3%, FVIII=184.3 % and Fibrinogen=349.5mg/dl which is agreed with the international reference value of FFP in quality control of blood banks, while the mean volume for the studied FFP was 118ml which is less than the international reference value.

Keywords: Factor V, Factor VIII, fibrinogen, fresh frozen plasma.


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