European Journal of Biomedical and Pharmaceutical Sciences

EFFECTS OF NEO VITACAINTM IN STELLATE GANGLION BLOCK

Tomoki Nishiyama*

ABSTRACT

The purpose of this study was to compare prospectively the effects of Neo VitacainTM (dibucaine 5 mg (0.1%), sodium salicylate 15 mg (0.3%), and calcium bromide (0.2%)) with local anesthetics in stellate ganglion block (SGB). Thirty patients scheduled for stellate ganglion block for post herpetic neuralgia were enrolled. Fifteen patients received SGB with Neo VitacainTM 5 mL for the first 5 times, then changed to the SGB with 1% lidocaine 5 mL for the next 5 times. Another 15 patients received SGB with 1% lidocaine 5 mL for the first 5 times, then changed to the SGB with Neo VitacainTM 5 mL for the next 5 times. Blood pressure, heart rate, pain as accessed by the visual analog scale (VAS, 0 – 100) and appearance of Horner syndrome and hoarseness were compared between lidocaine and Neo VitacainTM. Blood pressure and heart rate did not change significantly with both Neo VitacainTM and lidocaine. VAS score decreased without any differences between Neo VitacainTM and lidocaine. The number of the Horner sign was smaller with Neo VitacainTM, but not statistically significant. The number of the hoarseness was significantly lower with Neo VitacainTM than lidocaine In conclusion, SGB with Neo VitacainTM and lidocaine showed similar analgesic effects on post herpetic neuralgia and Neo VitacainTM induced less hoarseness than lidocaine.

Keywords: stellate ganglion block, dibucaine, sadium salicylate.