COLEUS FORSKOHLI (MAKANDI) AND ITS THERAPEUTIC EFFECT: A REVIEW
*Arti Sharma, Dr. Alankruta R. Dave, Om Pandey and Jitendra Varsakiya
ABSTRACT
Hypertension now becomes a global epidemic problem. It is truly called ―silent killer‖. Hypertension usually does not cause symptoms. Despite extensive research over the past several decades, etiology of most cases of adult hypertension is still unknown, and control of blood pressure is suboptimal in general population. Due to the associated morbidity and mortality and cost of society, prevention and treating hypertension is an important public health challenge. Globally, an estimated 26% of the world‘s population has hypertension, and the prevalence is expected to increase to 29% by 2025, driven largely by increase in economically developing nations. Ayurvedic medicines have favorable antihypertensive effect, but due to presence of antioxidant and ionotropic property of Coleus forskohli it may help to control hypertension along with the complication. In Coleus forskohli main constituent is Forskolin which shows the antihypertensive property. This review article will discuss about the chemical composition, morphology, pharmacology and therapeutic effect on various diseases with the help of different experimental trial, clinical trial, books, journal which are present on internet sources. A Pubmed database search revealed 85 Article on entering key word Coleus forkohlii, 150 related article are found from Google scholar, whereas Dhara online reveals no results on entering the key word Coleus forkohlii. 2 full papers are searched from Ayujournal.org.
Keywords: Coleus forkohlii, Makandi, epidemic, Hypertension, Anukta Dravya.
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