DEVELOPMENT OF DYSLIPIDEMIA IN PSORIASIS PATIENTS.
*Oluseyi Abidoye, Olaolu Lediju, Zarfishan Zahid, Raheel Naseeruddin, Pranav Patel, Milisha Lal, Vrushali Dhongade, Harsh Chapadia, Rono Korra, Abhishek Vadher and Himadri Vakharia
ABSTRACT
Background: Psoriasis is an autoimmune disorder with skin involvement. Psoriasis can lead to increased risk of incidence of cardiovascular morbidity and mortality. Some studies have showed that this can be due to the development of dyslipidemia. In this study, we tried to compare the lipid profile in patients with active lesions of psoriasis and healthy controls. Methods: In this study, we took a total of 35 patients with active skin lesions of psoriasis. 35 healthy individuals without any complaints were also taken. Psoriasis patients without any active skin lesions were excluded. Patients with any co-morbid conditions like diabetes, thyroidism, ihd, obesity, family history of hyperlipidemia were excluded. All values were calculated by student t test. Results: Patients with active psoriasis had higher levels of total cholesterol, trigylcerides, LDL-cholesterol and VLDL cholesterol when compared to the control population. However, there was no difference in the levels of HDL-Cholesterol in the psoriasis patients and control group. Conclusion: Psoriasis leads to increase in total cholesterol, trigylcerides, LDL-Cholesterol and VLDL-Cholesterol.
Keywords: cholesterol, trigylcerides, LDL-cholesterol and VLDL cholesterol.
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