European Journal of Biomedical and Pharmaceutical Sciences

PHARMACOGNOSTICAL AND PHYTOCHEMICAL EVALUATION OF TRAYODASHANGA GUGGULU VATI: AN AYURVEDIC POLYHERBAL FORMULATION

Dr. Madhuri Rai*, Dr. Harisha C. R., Dr. Shukla V. J. and Dr. T. S. Dudhamal

ABSTRACT

Introduction: Trayodashanga Guggulu Vati, is Guggulu based hearbal formulation .It provides strength to the nerves, bones, joints, muscles and ligaments. It is effective in all types of diseases related to nervous system and musculoskeletal system. Though Trayodashanga Guggulu Vati is Vatasamaka Rasayana, Balya, Amapachana, Rejuvenating property but till date, its pharmacognostical and pharmaceutical study has not been carried out. Aim: Authentication of raw drug of Trayodashanga Guggulu Vati and phytochemical evaluation of finished product. Materials and Methods: The present study deals with the pharmacognostical identification of the ingredients of Trayodashanga Guggulu Vati and its physicochemical analysis. Results: Powder microscopy revealed the presence of annular vessels of Shatavari, border pitted vessel of Guduchi, stone cells of Babbula, stone cells of Vraddadaru, starch grains of Shunti, etc., Physicochemical parameters such as total ash value (16.1%), water soluble extract (24.3%), methanol soluble extract (16.8%) were assessed in preliminary physicochemical scanning. High‑performance thin layer chromatography (HPTLC) revealed maximum 9 spots in short wave ultraviolet (UV) 254 nm. And four spots were obtained in long wave UV 366 nm. Conclusion: Pharmacognostical study revealed genuinity of raw drugs. Physicochemical and HPTLC studies inferred that the formulation meets the minimum as per quality standards.

Keywords: HPTLC, pharmacognosy, physicochemical analysis, Trayodashanga Guggulu Vati.