European Journal of Biomedical and Pharmaceutical Sciences

EVALUATION OF ANTIHYPERTENSIVE DRUGS IN PEDIATRIC POPULATION

*Svjetlana Loga Zec, Tarik Jarko?, Nataša Loga Andriji?, Amela Džubur-Ali?, Azra Metovi?, Jasmin Mušanovi? and Alma Džubur-Kulenovi?

ABSTRACT

Prevalence of pediatric hypertension is rising, primarily because of concomitant rise in the prevalence of obese children. Pediatric hypertension represents child's blood pressure greater than 95th percentile in respect to age, gender and height. Aim: Matherials and Methods: The study was designed as an observational, analytical, cohort study. It took place from February to July 2015 at the Pediatric Clinic CCU Sarajevo's Department of Cardiology and included a total of 82 patients. Results and Discussion: The most important parameters investigated were measurements of blood pressures in 3 therapeutic groups – patients implementing hygienic-dietetic regimen, patients solely on drug therapy, as well as patients on combined therapy (drug therapy and hygienic-dietetic regimen) – collected through measurements using sphygmomanometer and 24h ambulatory blood pressure monitoring. Most commonly used drugs were angiotensin converting enzyme inhibitors, beta-blockers, diuretics and calcium channel blockers. Conclusion: Implementing hygienic-dietetic regimen, drug therapy, as well as combined therapy leads to normalisation of blood pressure in children, and can prevent the progress of pediatric hypertension into adulthood.

Keywords: Hypertension, pediatric population, drug therapy.