European Journal of Biomedical and Pharmaceutical Sciences

CORRELATION OF FINE NEEDLE ASPIRATION CYTOLOGY WITH HISTOPATHOLOGY IN THYROID LESIONS

Dr. Huidrom Jyotsna Devi* and Dr. B. O. Parijatham

ABSTRACT

Introduction: The thyroid gland is the largest of all endocrine gland. Fine Needle Aspiration Cytology (FNAC) proves as an important investigation for proper identification and management of wide spectrum of thyroid lesions. The aim of the present study is to determine the accuracy of FNAC in detection of thyroid lesions at our institute. Objectives: The present study aims to classify various cytomorphological lesions of FNAC thyroid and correlate with histopathological findings. Material & Methods: This retrospective study was conducted from May 2015 – April 2016 in Pathology department of SBMCH, Chennai. Aspiration was taken after detailed clinical history, physical examination and thyroid function test, USG. Various lesions diagnosed by FNAC were correlated with histopathological findings wherever applicable. Results: Of 92 cases, 88 cases were female and 4 cases were male. Peak incidence was in the fourth decade and median age was 38 years .By Fine Needle Aspiration Cytology, of the 92cases, 90 cases(97.8%) were benign and 2 cases(2.17%) were malignant. Incidence of various thyroid lesions according to Fine Needle Aspiration cytology were Hashimoto thyroiditis 25 (27.1%) nodular colloid goiter with cystic changes 21(22.8%), colloid goiter43 (46.7%) thyroiditis 3(3.2%).Of the 92 cases, 23 cases were sent for histopathological study, 22 cases correlated with FNAC finding and 1 case diagnosed as nodular colloid goiter on FNAC turned out as papillary carcinoma thyroid on histopathology. Conclusions: FNAC is a safe, simple, highly accurate, economical and universally accepted modality for evaluation of thyroid lesions. FNAC helps in avoiding unwanted surgeries in patients diagnosed to have a benign pathology based on cytology.

Keywords: Thyroid, FNAC, nodules.