European Journal of Biomedical and Pharmaceutical Sciences

EVALUATION OF ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITY OF FICUS CARICA (MORACEAE) LINN

Rohtash Singh*, Mangal Sain Hooda, Neenalchal Trivedi and Krishna Mohan

ABSTRACT

Plants used in traditional medicine are potential sources of new biologically active compounds with innumerable therapeutic activities. Ficus Carica L. (Moraceae) is such plant used in myths medicines for a number of ailments. The research work to be started with the preparation of successive extract of plant in petroleum ether and ethanol respectively followed by pharmacological investigations including Organoleptic property and qualitative photochemical analysis of leaves of Ficus Carica showed the presence of triterpenoids, Glycosides, Alkaloids, Flavonoids, Tannins, Carbohydrates & proteins. The percentage yield values for petroleum ether, chloroform and ethanolic leaves extract were found to be 5.6%, 6.2% & 4.2% respectively. The obtained extract was used to carry out antioxidant study. Ficus carica leaves extract exhibited antioxidant activity when subjected to the tests like DPPH, hydrogen peroxide radical scavenging & reducing power assays. The obtained results (IC50) value were for DPPH free radical scavenging assay (2133.61μg/kg), Hydrogen peroxide radical scavenging test (12.93μg/ml), and reducing power assay (974.64μg/ml).

Keywords: Antioxidant, DPPH, Free Radical Scavenging, Anjeer.