European Journal of Biomedical and Pharmaceutical Sciences

EVALUATION OF ANTIMICROBIAL ACTIVITY OF CYMBOPOGON CITRATUS AGAINST CLINICALLY BURN WOUND ASSOCIATED SELECTED GRAM POSITIVE AND GRAM NEGATIVE BACTERIA

Tariq Ahmad Lone*

ABSTRACT

Microbial diseases are caused due to infectious bacterial pathogenic agents. Bacterial resistance is a growing problem worldwide different extracts from traditional medicinal plants were tested and some natural products were approved as new antibacterial drugs. Medicinal plants represent a rich source of antimicrobial agents are used medicinally in different countries and a source of many potent powerful drugs. There is still an urgent necessity to identify novel substances active against pathogens with higher resistance. The objective taken to find the effectiveness of essential oil of lemongrass for the treatment of pathogenic organisms. The extract was prepared from Cymbopogon Citratus by using ethanol and water. Cymbopogon Citratus plant extract was successfully done to evaluate the antibacterial activity for the burn wound isolates of gram positive bacterial strains Bacillus subtilis, Staphylococcus aureus, Streptococcus faecalis, Streptococcus pyogenes, Enterococcus faecalis and gram negative bacterial strains of Escherichia coli, Pseudomonas aeruginosa, Enterobacter aerogenes, Klebsiella aerogenes, Citrobacter freundii respectively. The assay was done to measure the zone of inhibition for the antimicrobial activity at significant extent. The ethanolic and water extracts of Cymbopogon citratus shows remarkable effective antimicrobial property against both gram positive as well as gram negative bacteria such as Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis Escherichia coli, Pseudomonas aeruginosa, Enterobacter aerogenes and Klebsiella aerogenes. But it also found out that both ethanolic and water extracts of Cymbopogon citratus does not inhibit the Citrobacter freundii, Streptococcus faecalis and Streptococcus pyogenes.

Keywords: Cymbopogon Citratus, Gram positive bacteria, Gram Negative bacteria, Antimicrobial activity.