Abstract
ANTIUROLITHIATIC ACTIVITY OF ETHANOLIC DOLICHOS BIFLORUS LEAF EXTRACT

Pragati Khare*, Pranit Saraswat and Noopur Khare

ABSTRACT

Objective: The objective of this study is to investigate the antiurolithiatic potential of ethanolic Dolichos biflorus L. leaf extract in swiss albino mice. Methods: The antiurolithiatic potential of Dolichos biflorus L. ethanolic leaf extract was investigated by using Zinc disc foreign body insertion technique model. Antiurolithiatic activity of the leaves was evaluated on the basis of decrease in the weight of stones. 36 swiss albino mice of either sex weighing between 25-30gm were randomly selected and divided into 6 equal groups. Group-I received Prophylactic control (1% ethylene glycol for 4 weeks), Group-II received Prophylactic treatment (1% ethylene glycol + ethanolic extract of leaves of Dolichos biflorus 400 mg/kg orally for 4 weeks), Group-III received Prophylactic treatment (1% ethylene glycol + ethanolic extract of leaves of Dolichos biflorus 800 mg/ kg orally for 4 weeks), Group IV received Curative control (1% ethylene glycol for 4 weeks followed by water for 4 weeks), Group V received Curative treatment (1% ethylene glycol for 4 weeks followed by ethanolic extract of leaves of Dolichos biflorus 400 mg/kg for 4 weeks) and Group VI received Curative treatment (1% ethylene glycol for 4 weeks followed by ethanolic extract leaves of Dolichos biflorus 800 mg/kg for 4 weeks). Results: It was observed that there was significant decrease in the weight of the stones in the groups treated with leaf extract of Dolichos biflorus in comparison to the control group. Conclusion: The results of the present study indicate that ethanolic extract of Dolichos biflorus possesses significant Antiurolithiatic activity.

Keywords: Dolichos biflorus leaves, Antiurolithiatic activity, urinary bladder.


[Full Text Article]   [Download Certificate]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: MAY ISSUE PUBLISHED

    MAY 2024 Issue has been successfully launched on 1 MAY 2024.

  • EJBPS New Impact Factor

    EJBPS Impact Factor has been Increased to 7.482 for Year 2024.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT