Abstract
DETERMINATION OF SELECTED TRACE ELEMENTS AMONG CHILDREN WITH SICKLE CELL ANEMIA IN ELOBIED CITY - NORTH KORDOFAN STATE

Akram Hamed Awad Alla Elsukar*, Waleed Hajmusa Elttahir, Osman Abd Algadir and Reham Elsheihk Omer

ABSTRACT

Introduction: Sickle cell anemia is a genetic hemoglobin disorder characterized by chronic hemolysis. Severe hemolysis affect blood component include trace element (zinc & cooper). Objectives: to estimate zinc and copper minerals in children with sickle cell anemia enrolled in Sudan Sickle Cell Anemia Center in North Kordofan State during the period from April – August 2016. Materials & Methods: This descriptive cross-sectional study. A total number of 30 blood samples collected from children with sickle cell anemia aged 5 - 40 months (14 male & 16 female). Zinc and copper estimated by atomic absorption spectrophotometry, and compared with 20 apparently healthy volunteer as control group age & sex- matched for test group. Statistical package for social science (SPSS version 15) computer software was used for data analysis. Results: a significant decreased in serum zinc and copper among test group when compared with control group. (P.value = 0.03 and 0.05) respectively; with no significant difference between male & female among test group. Conclusion; the current study indicates that determination of trace elements is of value for children with SCA since their serum levels were significantly decreased.

Keywords: Trace elements, Sickle cell anemia, Elobied.


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