Abstract
NANOPARTICLES IN DRUG DELIVERY AND CANCER TREATMENT: LATEST ADVANCEMENT

Rahul Kumar Singh, Ritesh Kumar Tiwari* and Richa Saxena

ABSTRACT

Nanoparticles are 1–100 nanometers in size. These particles can be used in a targeted drug delivery approach, as they can specifically target a drug or drug carrier to minimize drug-originated systemic toxic effects Nanotechnology has the potential solutions to these current obstacles in cancer therapies because of its unique size and large surface-to-volume ratios. Nanoparticles have properties of self-assembly, stability, specificity, drug encapsulation and biocompatibility as a result of their material composition. Nanoparticle-mediated targeted delivery of drugs significantly reduces the dosage and optimize their release properties, increase specificity and bioavailability, improve shelf life, and reduce toxicity. In treatment of cancer, the medicine use as nanoparticles drug delivery systems has advanced in the bioavailability, in vivo stability, intestinal absorption, solubility, sustained and targeted delivery, and therapeutic effectiveness of several anticancer agents. In this review, In this review, we focus on the current advancement in nanoparticle drug delivery systems for treatment of cancer.

Keywords: Nanoparticles, Cancer therapy.


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