VARIATIONS OF RED BLOOD CELL INDICES IN SICKLE CELL ANEMIA W. S. R TO PANDU
Dr. Rajeev Kumar*, Dr. Ketki Aurangabadkar and Dr. Sachin Deva
ABSTRACT
Sickle Cell Disease (SCD) is a most important and widely prevalent haemoglobinopathy which is due to the presence of Sickle Haemoglobin (Hb S) in Red Blood Cell. Red cell develops sickling when they are exposed to low oxygen tension. It is typically inherited from an individual’s parent (autosomal recessive). This disease is characterised by chronic Haemolytic Anaemia. Changes in Red Blood Cells can be observed and interpreted from a well furnished report of Red Blood Cell Indices. Red Blood Cell indices include PCV, MCV, MCH, MCHC and RDW. Ayurveda texts has not explained Sickle Cell Disease directly, rather explained it as Pandu Rog with the symptoms like Raktalpta (low Haemoglobin), Aruchi (Anorexia), Daurbalya (debility), Shwas (Dyspnoea), Jwar (Fever), Shoola (Pain) etc. It can be correlated with Sickle Cell Anemia due to the fact that many of the symptoms that are mentioned in Pandu Rog are similar to the symptoms mentioned in sickle cell disease. Further in this Article variations of Red blood cells Indices in Sickle Cell Anaemia w.s.r to Pandu will be highlighted.
Keywords: Sickle Cell Anaemia, Red Blood Cell indices, PCV, MCV, MCH, MCHC, RDW, Pandu, Anuman Praman.
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