European Journal of Biomedical and Pharmaceutical Sciences

A REVIEW ON ROLE OF AMA IN THE PATHOGENESIS OF DISEASE

S. N. Tiwari*

ABSTRACT

The concept of Ama is unique to Ayurveda. Which acts as underlying cause of various disorder. Many factors play an important role in the production of Ama but in ayurveda, pragyaparadha act as a chief contributory factor. The term Ama means unripe or undigested food material.[1] Vagbhatta firmly believe that due to hypo-functioning of Agni the first Dhatu viz. the Rasa or chyle is not properly formed, instead the Annarasa undergoes fermentation or putrefaction being retained in Amashaya. It is a state of Rasa which is called as Ama.[2] By observing of different Samhita, few valuable and occult concepts comes into light which contribute Ama formation such as Mandagni, Dhatwagni-mandya and Mala Sanchaya etc. These factors facilitate Amotpatti and participate in the pathogenesis of several disorders such as Amajeerna, Vidagdhajeerna, Vistabdhajeerna ,Jwara, Atisara, Grahani Dosha and Amavata etc.[3] In the other hand the text of modern science states that due to disequilibrium of digestive juices, an oxidants (Ama) is produced which is a toxic byproduct & its peak level triggers the pathogenesis of different disorder.

Keywords: Pragya Paradha, Agni, Dhatwagnimandya, Oxidants, Ajeerna.