Abstract
PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND PHARMACOGNOSTIC EVALUATION OF ALTERNANTHERA SESSILIS (LINN.) R. BR. EX DC.

Alok Kumar, Abhishek Kumar, Ravindra Singh, Pawan Ahirwar, *Manoj Kumar Tripathi

ABSTRACT

Alternanthera sessilis (Linn.) R. Br. ex DC. is a small prostrate perennial herbs belongs to family Amaranthaceae, widely used to treat the diabetes and skin diseases and also other various ailments. All the part of this plant are reported for various ethnomedicinal and therapeutic uses.Vegetative aerial parts viz. root, leaf and stem were collected in various seasions and studied for macroscopical, anatomical, physicochemical and preliminary phytochemical, fluorescence and HPTLC studies. Microscopically root of Alternanthera sessilis (Linn.) R. Br. ex DC. Showed presence of cork cells in surface view, reticulate thickening. Stem showed spiral and annular thickening, phloem fibres, cortical parenchyma filled with starch grains and rosette crystals of calcium oxalate, thick walled cork cells, collenchymatous cells, leaf showed palisade cells, cluster crystals of calcium oxalate, prismatic crystals of calcium oxalate, lower epidermis with stomata, upper epidermis with stomata, fragments of trichome characteristics feature of the family Amaranthaceae. Phytochemivcally, the various extract showed the presence of diverse phytochemicals such as alkaloids, phenolic compounds, carbohydrates, saponin steroids and triterpenoids tannin, proteins flavanoids content as compare to root and stem. The physicochemical analysis explored the loss on drying at 105oC , water soluble extractive value, alcohol soluble extractive value, Total ash value, acid insoluble ash value, Phytochemicals were evaluated for the plant Alternanthera sessilis (Linn.) R. Br. ex DC. Using HPTLC fingerprinting.

Keywords: Phytochemical, Alternanthera sessilis, Physicochemical analysis, Macroscopy, HPTLC fingerprinting.


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