Abstract
PROTECTIVE ROLE OF SOLANUM NIGRUM LINN LEAF METHANOL EXTRACT ON MALE WISTAR ALBINO RATS AGAINST N-NITROSODIETHYL AMINE INDUCED HEPATOCARCINOMA

Pandurangan Ayyanar, Rajenderan Murugan and Natesan Manoharan*

ABSTRACT

The protective role of Solanum nigrum Linn. was studied in N-nitrosodiethyl amine induced hepatocarcinoma on Wistar albino male rats. The haematological content RBC count, WBC count, Platelet count, PCV, Hemoglobin and ESR were studied and results showed significant (P≤0.001) increased production was recorded. In addition to that liver markers enzyme serum glutamate pyruvate transaminase, serum glutamate oxaloacetic transaminase, acid phophatase, alkaline phophatase, lactate dehydrogenase and γ-glutamyl transpeptidse, and serum biochemical parameters, bilirubin, creatinine, urea, uric acid and serum protein were analyzed. The lipid peroxidation (LPO) and lipid profile were also estimated along with histopathological study in liver tissue. All the parameters are statistically calculated at P≤0.001, P≤0.01and P≤0.05. The recorded results showed significant revert changes in experimental liver tissue.

Keywords: Hepatocarcinoma, Solanum nigrum, N-nitrosodiethyl amine.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: JUNE ISSUE PUBLISHED

    JUNE 2023 Issue has been successfully launched on 1 JUNE 2023.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT