European Journal of Biomedical and Pharmaceutical Sciences

FAMILY HISTORY AS MAJOR PREDISPOSING FACTOR IN VARICOSE VEINS DISORDER

Shiksha Sharma*, Minakshi Vashist and Madan Gopal Vashist

ABSTRACT

Varicose veins of lower extremities is a very frequent problem that affecting most of the men and women and children also. Several risk factors have been associated with the development of varicose veins, namely age, female sex, obesity, and possibly family history. Family history is proven to play an important role in the occurrence of varicose veins disease. In the present study role of family history in the patients of varicose veins has been analysed. Information regarding occurrence of varicose veins was collected from 216 patients and their family members. The data included, age of diagnosis, body mass index, occupation and family history of disease. Analysis of 216 patients revealed 132 patients with family history of varicose veins. In present study it was found that the occurrence of varicose veins was more frequent in patients with a positive family history mainly paternal influence. Out of above mentioned 132 patients, 68 patients had two person from their family affected with varicose veins and 53 patients had more than 3 persons affected with varicose veins. Adjusted OR was 6.375 (95% CI: 0.7508-54.126) in male and 0.319 (95% CI: 0.0319-3.181) in female. Evaluation of patients of varicose veins and their family members revealed, family history as an important major risk factor in occurrence of varicose veins. The information may improve the knowledge of people regarding varicose veins and to take preventive measures in advance.

Keywords: Family history, Risk factor and varicose veins.