European Journal of Biomedical and Pharmaceutical Sciences

CLINICAL PROFILE AND EVALUATION OF PATIENTS OF CARCINOMA ESOPHAGUS AT AVBRH

Akshay Bora*, Meenakshi Yeola, Chandrashekhar Mahakalkar, Tanu Pradhan, Aniket Khadatkar,
Anunay Kumar and Pratik Abhishek

ABSTRACT

Introduction - Esophageal carcinoma is a malignant disease seriously threatening human health and lives. In 2012, it was estimated that 455,800 new cases and 400,200 deaths from esophageal cancer occurred in the whole world, which ranked the eighth in incidence and the sixth in mortality of cancers.[1] In India, according to data from the National Cancer Registry, esophageal and gastric carcinomas are the most common carcinomas found in men, while esophageal cancer ranks third in women after carcinoma of breast and cervix. Aim and objectives - To study the clinico-pathological co-relation of patients of carcinoma esophagus. To study the demographic profile of patients of carcinoma esophagus admitted at AVBRH. To study the mode of presentation. To study the etiological factors. To study the endoscopic findings. To study the co-relation with the histo-pathology. Methods - This is a prospective observational study of patients diagnosed as carcinoma esophagus at Acharya Vinoba Bhave Rural Hospital, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, a 1280 beded tertiary, rural, university affiliated teaching hospital in central India, from July 2015 to October 2017 with a sample size of 50 patients. Results – The study demonstrated that esophageal cancer was found mostly in females (56%) rather than males (44%). Dysphagia was the most common presenting complaint followed by weight loss. Squamous cell carcinoma was far more common than adenocarcinoma. The incidence of metastasis was 30% in the study. Conclusion - Carcinoma esophagus is a fatal malignancy owing to high rate of metastasis at the time of diagnosis of the condition. Any patient presenting above age of 50 years with symptoms of progressive dysphagia should undergo flexible endoscopy of upper gastrointestinal tract. In case of suspected lesions biopsy from the lesion should be taken and patient needs to be subjected for further radiological evaluation like CT Thorax.

Keywords: To study the co-relation with the histo-pathology.