Abstract
CORRELATION OF 2D:4D RATIO AND CORONARY ARTERY DISEASE: A STUDY IN NORTH INDIAN MALE POPULATION

Vikramjeet Singh, Reena Singla* and Nidhi Puri

ABSTRACT

Background: Human 2D:4D ratio attract considerable research interest because they exhibit sexual dimorphism and are linked to several traits.The objective of this study is to find whether 2D:4D ratio could be used as a marker for predisposition to CAD as assessed by coronary angiography in north Indian male population. Material and Methods: This study includes 200 males; 100 subjects with CAD and 100 subjects without CAD between age 18-80 years. Finger lengths were measured twice for both hands using digital caliper. The results were tabulated and subjected to statistical analysis. Results: 2D: 4D ratio was found more in men with CAD & p value was statistically significant. Cohen’s effect size was small for right and medium for left hand. Conclusion: The present study supports a positive correlation between high 2D:4D ratio and CAD in males. High 2D:4D ratio is predictive of CAD and may be used in diagnosis and in early life style intervention in Indian men.

Keywords: Finger length ratio; 2D:4D ratio; CAD-coronary artery disease.


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