CLINICO EPIDEMIOLOGIC STUDY OF ADULT PATIENTS PRESENTING WITH NEW ONSET BRONCHIAL ASTHMA IN NEPAL
Chhetri Roshan*, Bhatta Narendra, Pradhan Bickram and Koirala Puru.
ABSTRACT
Background: Despite being one of the most common respiratory disesase, the epidemiological and clinical
aspects of the bronchial asthma varies in different parts of the world. This study is done to find out if there are any
specific patterns of the disease in relation to clinical features, risk factors, severity, triggers, and socio
demographic factors. Methods: Ninety five patients were enrolled in this study based on clinical diagnosis of
bronchial asthma as per case definition of Global initiative for Asthma (GINA) from March 2014 to April 2015.
All the detail data of risk factors, triggers, symptoms and data from investigations like pulmonary function test,
chest radiographs, sputum profile, absolute eosinophil count and hs-C reactive protein were collected. Results: We
observed female predominance with 69.5% with median age of 40.04 years. 38.9% of patients had history of
significant exposure to indoor air pollution. Cough (87.4%) was the most common clinical symptom on
presentation and wheeze (81.1%) was the most common clinical examination finding. Most of them (44.2%)
presented with mild persistent bronchial asthma and 76.8% of study population had upper respiratory tract
infections as triggering factor. C reactive protein was elevated in 58.9% and Absolute eosinophil count was raised
in 42.1% of patients. Conclusion: Yonger age, female with exposure to indoor air pollution are more prone for
adult onset bronchial asthma which is usually triggered by upper respiratory tract infections, mostly presented with
cough and wheeze and elevated C reactive protiens and absolute eosinophil counts.
Keywords: Asthma, clinic-epidemiolgical, Nepal.
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