SCREENING OF LAMPRACHENIUM MICROCEPHALUM AN ENDEMIC PLANT OF ASTERACEAE FROM WESTERN GHATS OF INDIA FOR THEIR PHENOLS, FLAVONOIDS AND ANTIOXIDANT PROPERTIES
Rahul Mane, Prashant Anbhule, Sujata Patil and Vinod Shimpale*
ABSTRACT
At the present there is a growing interest of pharmaceutical industries to replace synthetic chemicals by expected products with bioactive properties that are of plant source. The aim of present study was to evaluate the endemic medicinal plant Lamprachaenium microcephalum Dalz. Benth. of Western Ghats of India for their Phytochemicals, antioxidant properties and to determine phenolic compounds by reverse-phase high performance liquid chromatography in three different solvent systems. It is noted that solvents significantly affects the quantity of Phytochemicals and antioxidant properties. In the species total phenol content (TPC) was highest in methanol extract and lowest in acetone extract and same trend was observed for the total flavonoid content (TFC). All the extracts of the species showed 2, 2-diphenyl-1-picrylhydrazyl (DPPH), Reducing power and Hydrogen peroxide free radical scavenging activity (H2O2). The results showed that among studied antioxidant activities acetone extract of both the species showed highest Hydrogen peroxide free radical scavenging activity L. microcephalum 78.37%. The results provide explanation for the use of this plant in folk medicine to treat various diseases.
Keywords: Phytochemicals, antioxidant properties, endemic, medicinal plants W.G.
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