European Journal of Biomedical and Pharmaceutical Sciences

GC-MS, PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITIES OF FRUIT PULP OF AEGLE MARMELOS (L.) CORRÊA

S. P. Vardhini, *Sivaraj C., Himanshu Ranjan and Arumugam P.

ABSTRACT

The present work describes the phytochemical analysis, antioxidant activities of ethanol extract of the fruit pulp of Aegle marmelos. It is also known as bael, which is an important medicinal plant which belongs to family Rutaceae. Compounds purified from A.marmelos have been proven biologically active against various several major diseases like cancer, diabetes, cardiovascular diseases. The aim of the present study was to evaluate the antioxidant activities of ethanol extract of fruit pulp of A. marmelos and to identify the bioactive compounds by GC-MS analysis. Antioxidant activities such as DPPH radical, ABTS•+ radical cation, Fe3+ reducing power and phosphomolybdenum reduction assays were carried out for ethanol extract. The maximum DPPH radical and ABTS•+ radical cation scavenging activities of ethanol extract were 89.58±6.27% at 300 μg/mL and 92.19±6.45% at 30 μg/mL concentration. The IC50 values of DPPH˙ radical and ABTS•+ radical cation scavenging activities were 84.14 μg/mL and 9.67 μg/mL concentration. The maximum reduction of Fe3+ and Mo6+ were 67.80±4.74% and 85.93±6.01% at 120 μg/mL concentrations and the IC50 values were 63.84 μg/mL and 21.05 μg/mL concentrations respectively.

Keywords: Aegle marmelos, TLC, DPPH, ABTS·+, GC-MS.