Abstract
ASSOCIATION BETWEEN MALARIA PARASITE INFECTION AND PLASMA VWF LEVEL AMONG SUDANESE PATIENTS IN KHARTOUM 2017

*Khatab Mohamed Elfaki and Ibrahim Khider Ibrahim

ABSTRACT

Von Willebrand factor (VWF) is a large sialoglycoprotein, which circulates in normal plasma as a series of heterogeneous multimers and plays a critical role in primary hemostasis by mediating platelet adhesion to exposed collagen at sites of vascular injury. This study aimed to evaluate the vWF level among Sudanese malaria patients. A total of 40 samples were collected (23 males and 17 female) from malaria patients (27 with P.falciparum and 13 with P.vivax). The vWF level was measured using Enzyme linked immunosurpent assay (ELISA) .Data was analyzed by statistical package for social science (SPSS). The results of the current study showed that there is no significant association between malaria infection and plasma vwf level (P-value: 0.148). According to our result there is no association between malaria infection and plasma vwf level.

Keywords: Von Willebrand factor, Malaria.


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