European Journal of Biomedical and Pharmaceutical Sciences

A STUDY ON ESCHERICHIA COLI RESISTANCE TOWARDS ANTIBIOTIC IN KERALA STATE.

Shaji George*, Rakesh Kumar Jat and Sree Janardhanan Vaidyanathan

ABSTRACT

The study on resistance pattern of microbes in respect to antibiotics, by observing the sensitivity pattern was conducted on 1000 patients reported with infection in Kerala population. The observation made, reveals that the maximum number of patient showing up with some sort of infections belonged to middle age group or geriatric group, particularly the age between 41 to 80 years. The female patients representation (70.3%) was observed as the highest when compared to the males (29.7%) with infection. On observing the type of samples which usually make up for sensitivity test or analysis, it was found that the urine sample with 81% female representation indicated higher urinary infections. On analysing the E. coli involvement in developing disease it was estimated to be 57%. The drugs like Amikacin, ceftriaxone, ciprofloxacin etc. were some of the highly sensitive drugs and the drugs like Azithromycin, Cefoperazone-Sulbactum, Cephalexin etc. belonged to high resistant group indicating uselessness to treat infections.

Keywords: Antibiotic resistance, E. Coli, Sensitivity pattern, resistance pattern, Infections.