European Journal of Biomedical and Pharmaceutical Sciences

IMPACT OF IRON DEFICIENCY ANEMIA ON HEAMGLOBINA1C LEVEL AMONG SUDANESE PATIENTS

Musa Abdelhaleem Alahaj Musa, Nassr Eldin M. A. Shrif and Abdelgadir Eltom*

ABSTRACT

Background: Iron deficiency anemia is the most occurring form of anemia in Sudan. Hemoglobin A1c (HbA1c) is used in diabetic patients as an maker to reflect glucose levels of the last 3 months. Like blood sugar levels HbA1c levels are also affected by presence of variant hemoglobin, hemolytic anemia, nutritional anemia’s, uremia, pregnancy and acute blood loss. However, reports on the effects of iron deficiency anemia on HbA1c levels are inconsistent. We conducted this a study to analyze the effects of iron deficiency anemia on HbA1c levels. Objectives: The aim of this study the impact of iron deficiency anemia on hemoglobin A1c level among Sudanese patients. Methods: Cross sectional case control study Fifty patients confirmed to have iron deficiency anemia were enrolled in the study. These values were also compared with those in the control population. Results: The mean baseline of HbA1c level in anemic patients (7.10) was significantly higher than that of controls (3.9). Conclusion: Iron deficiency anemia has a direct correlation with HbA1c levels and the relationship is in verse between them. This signifies that as the level of hemoglobin drops with increasing severity of iron deficiency in anemic subjects, at the same time HbA1c levels increase correspondingly. Moreover, with correction of iron deficiency in the anemic subjects, the HbA1c levels decline to near normal values. Other than blood glucose, many other factors values. Iron deficiency anemia being extremely common in Sudan settings should always be ruled out when high HbA1c levels are detected and should be corrected on priority to achieve true levels of HbA1c.

Keywords: Iron deficiency anemia, Diabetes mellitus, Hemoglobin A1c.