COAGULATION PROFILE AMONG PREGNANT WOMEN WITH PREECLAMPSIA IN SUDAN 2018
Tarig A. M. Hamid*, Zeinab S. A. Alsayed and Elharam I. Abdallah
ABSTRACT
PE Is universally defined as hypertension and significant proteinuria developed at or after 20 weeks of pregnancy in an otherwise normotensive woman.PE having an increased risk for thrombosis. A prospective case control study was conducted in Bahri and Omdurman Maternity Hospital-Khartoum state; in a period of June to Nov 2017. Pregnant women’s who admitted into the Department of Obstetrics and Gynaecology or attended at antenatal care unit, were enrolled in the study. A total of 100 pregnant women’s; among them 50 patients with either mild or sever PE and 50 normal pregnancies as controls. Citrated venous blood samples were collected from each subject; platelet poor plasma was separated for measurement of prothombin time (PT), activated partial thromboplastin time (APTT) and thrombin time (TT) level using semi-automated analyzer also d dimer using ichrome .In the present study the mean of APTT and d dimer were found to be (42.23 ±6.47, 34.01 ± 4.80), (1751.69 ±1978.63, 294.12 ±101.49) of PE to normal pregnant respectively and (P; 0.00). While mean of PT, TT were found to be (15.20 ±2.2, 14.43 ± 1.60),(17.06 ±1.29,16.54 ±1.13) (P;0.54 ; 0.36 ) of PE to normal pregnant respectively. The APTT and d dimer increase in PE compared with normal pregnant, while there were no difference in PT and TT among two group in spite of it is prolonged level within majority of PE.
Keywords: PE Is universally defined Gynaecology prothombin majority of PE.
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