European Journal of Biomedical and Pharmaceutical Sciences

ANTIPSYCHOTIC POTENTIALS OF INDIAN HERBS: AN OVERVIEW

Monisha Bansal, Gurfateh Singh* and S. L. Harikumar

ABSTRACT

Psychosis is an intense mental disorder characterized by impaired thinking and emotions which indicate that the person experiencing them has lost contact with reality and affects about 1% of the population. It is characterized by a myriad of signs and symptoms which include distortion of thinking and perception, cognitive impairments, motor abnormalities, volition and apathy, difficulties in communication and restricted affective expression. Various allopathic medicines are available in market such as chlorpromazine, fluphenazine, triflupromazine, haloperidol, trifluperidol, penfluridol, flupenthixol, clozapine, resperidone. But prolonged exposure to antipsychotic medication has been associated with side effects & adverse event including extrapyramidal symptoms (EPS), tardive dyskinesia, an irreversible motor disorder, diabetes or metabolic problems, weight gain/obesity, heart problems, strokes, Parkinson’s disease, lack of efficacy, cognitive decline or impairment, brain shrinkage, seizures or convulsions, lowered bone mineral density, violence and homicidal ideation, psychosis and delusional thinking, tumors and brain defects which leads to increase mortality worldwide. Therefore the demand for herbal formulation is increasing day by day. This article enlightens about the various anti-psychotic Indian Herbs that can be applicable to abolish the drug induced side effects and improve the psychotic symptoms clinically.

Keywords: Psychotic, Herbal, Motor disorder, Thinking.