Abstract
PREPARATION, EVALUATION AND APPLICATION OF MUCOADHESIVE MICROSPHERES: A RESEARCH APPROACH TO NOVEL & TARGETED DRUG DELIVERY METHODS, INCORPORATION WITH MICRO TECHNOLOGY

Praveen Tahilani*, Ankita Kishore and Bhagyashri Gupta

ABSTRACT

Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers which are biodegradable in nature and ideally having a particle size less than 200 μm. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumor. In future by combining various other strategies, microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, gene & genetic materials, safe, targeted and effective in vivo delivery and supplements as miniature versions of diseased organ and tissues in the body.

Keywords: Microspheres, controlled release, Types of microspheres, Methods of preparation, characterization of microspheres, applications.


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