European Journal of Biomedical and Pharmaceutical Sciences

EVALUATION OF PHARMACEUTICAL PROFILE OF SHARAPUNKHADI YOGA – REMEDY FOR NON ALCOHOLIC FATTY LIVER DISEASE

Remya E.*, Mandip Goyal and V. J. Shukla

ABSTRACT

Non Alcoholic Fatty Liver Disease (NAFLD) is the disease of the era which arises mainly from faulty lifestyle. There is no established treatment for NAFLD in conventional medical science. Sharapunkhadi Yoga is a formulated combination comprising of equal quantities of extracts of Sharapunkha, Bhoomiamalaki and Katuki. Extracts of all the drugs have shown significant hepatoprotective activity in experimental study in rats. The formulation is one among the best remedies Ayurveda can offer for the management of NAFLD. Present study has been aimed to develop pharmaceutical standards and HPTLC fingerprints for individual ingredients and for Sharapunkhadi Yoga itself. Loss on drying, ash value, water and alcohol soluble extract were found to be within the permissible limits of Churna. Phyto-chemical evaluation had shown the presence of carbohydrates, steroids, glycosides, saponins, tannins and phenols. HPTLC study shows 5, 3 and 9 peaks for Sharapunkhadi Yoga at 254nm, 366nm & after visualization at 500nm respectively.

Keywords: HPTLC, Pharmaceutics, Physicochemical analysis, Sharapunkhadi Yoga, Non-alcoholic fatty liver disease.